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The upper panel shows microscopic photographs of the MCF-7 cancer cells in the absence (C) and presence of different concentrations of the Ni(II) complex (indicated by the number inside each photo).
(A)(A)tThe Ni(II) complex docked in the binding pocket of BSA using MVD. The complex depicted in a stick model, and the BSA represented in a wireframe model, (B) two-dimensional interactions generated by LIGPLOT+.
(A) Molecular docking perspective of the Ru (II) complex with the major groove side of DNA using MVD. The complex depicted in a stick model, and DNA, represented in a wireframe model, (B) two-dimensional interactions generated by LIGPLOT.
Treatment of K562 cells with the various oxicam complexes and the oxicam ligands showed different inhibition effects in a concentration dependent manner. The cell inhibition was measured after 48 h by the MTT assay.
Treatment of K562 cells with the various metal salts showed different inhibition effects in a concentration dependent manner. The cell inhibition was measured after 48 h by the MTT assay. Each data point represents the mean for three separate experiments
(A) (A)tThe docked trans-[Cu(Pir)2(THF)2] complex in the binding pocket of BSA using MVD. The complex is depicted in a stick model, with BSA represented in a wireframe model; (B) two-dimensional interactions generated by LIGPLOT+.
(A) The docked trans-[Co(Mel)2(EtOH)2] complex in the binding pocket of BSA using MVD. The complex is depicted in a stick model, with BSA represented in a wireframe model; (B) two-dimensional interactions generated by LIGPLOT+.
(A) (A)tA molecular docking perspective of trans-[Cu(Pir)2(THF)2] with the major groove of DNA using UCSF Chimera. The complex is depicted in a stick model, and DNA is represented in a wireframe model; (B) two-dimensional interactions generated byLIGPLOT+
Cancer Paper
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